Today is the second Sunday of the 2016 NFL Season and with it comes a full slate of exciting matchups.

San Francisco 49ers at Carolina Panthers 1:00pm FOX

Chip Kelly brings his brand of high flying offense into the home of Cam Newton and the reigning NFC Champion Panthers.

Baltimore Ravens at Cleveland Browns 1:00pm CBS

In what could quickly turn into an AFC North blowout, Jon Harbaugh’s Ravens smell blood in the water as they take the field to battle with a perpetually rebuilding Cleveland team reeling from the loss of starting quarterback Robert Griffin III.

Tennessee Titans at the Detroit Lions 1:00pm CBS

The Titans new, improved running game is looking to grind out a win against Matthew Stafford’s Lions.

Kansas City Chiefs at Houston Texans 1:00pm CBS

The rematch of last year’s AFC Wildcard blowout brings new faces in a high-powered Texans offense and lacks the turnover machine known as Brian Hoyer. Tune in for a possible preview of this year’s key playoff contenders.

Miami Dolphins at New England Patriots 1:00pm CBS

New coach Adam Gase takes his new look Dolphins north hoping to steal a win from the Tom Brady-less Patriots.

New Orleans Saints at New York Giants 1:00pm FOX

Drew Brees takes his new contract extension to do battle with fellow NFC Super Bowl Champion Quarterback Eli Manning and his Big Blue buddies.

 Cincinnati Bengals at Pittsburgh Steelers 1:00pm CBS

In what is becoming the nastiest rivalry in the NFL, Karlos Dansby and Adam Jones will try to slow down what may be the best offense in the league in. Will Ben Rothlisberger, Antonio Brown and DeAngelo Williams be fantasy kings once more?

Dallas Cowboy at Washington Redskins 1:00pm FOX

Yesteryear’s most relevant rivalry renews in the DC suburbs as rookie Dak Prescott tries to prove he can make Cowboy fans forget about Tony Romo. But Redskin QB Kirk Cousins may not like that.

Tampa Bay Buccaneers at Arizona Cardinals 4:05pm FOX

Jameis Winston tries to prove he’s a contender against an Arizona team trying to prove they were the better team last week when the lost to the Patriots.

Seattle Seahawks at Los Angeles Rams 4:05pm FOX

Pro football returns to the LA Coliseum for the first time since the 1990s. That’s right, many of the players taking the field today weren’t even alive the last time Los Angeles had an NFL home game.

Indianapolis Colts at Denver Broncos 4:25pm CBS

In what used to be a battle of the Peyton Manning teams, Andrew Luck will try to navigate the Super Bowl champion defense while the Colts D tries to stop rookie Quarterback Trevor Siemian from making them look bad.

Atlanta Falcons at Oakland Raiders 4:25pm CBS

Matt Ryan’s Falcons continue to struggle for an identity as they enter the Black Hole and battle a resurgent Oakland Raider team hungry for wins.

Jacksonville Jaguars at San Diego Chargers 4:25pm CBS

Two teams hoping to be in the AFC Wild Card discussion in December meet today to try and grab their first win of the 2016 season.

Green Bay Packers at Minnesota Vikings 8:00pm NBC

Sunday Night Football continues as the Packers make the first of many visits to the shiny new Minnesota stadium to take on the Teddy Bridgewater-less Vikings in an early season battle for control of the NFC North.